A RARE CASE OF SECONDARY AMENORROHEA WITH SWEYERS SYNDROME: A CASE REPORT

Sweyers syndrome or pure gonadal dysgenesis is characterised by primary amenorrhea , presence of female phenotype, external genitalia and internal with hypoplastic uterus streak gonads. A 16 year old girl presented secondary amenorrhoea, she attained menarche at 11 years was followed 4 months regular cycles thereafter developed two amenorrhea. On examination phenotypically no sexual characteristics, female. Laboratory investigations showed a high level serum follicle stimulating hormone, Luteinising hormone which were consistent hyper gonadotropic hypogonadism, pelvic ultrasound hypo plastic ovaries, chromosomal analysis revealed XY Karyotype. Further underwent alaparoscopic prophylactic gonadectomy the histopathology confirmed ovaries. In conclusion we emphasise that can present amenorrhoea functioning lining endometrium. The importance timely diagnosis forseeing gonadoblastoma cannot be over emphasised.